Anti-TNF11 Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K106545P-50ul	solarbio	50ul	960.00元
K106545P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-TNF11 Polyclonal Antibody
别名	CD254;hRANKL2;ODF;OPGL;OPTB2;RANKL;sOdf;TNLG6B;TRANCE
应用	WB
稀释比例	WB 1:3000.
交叉反应	Human Mouse Rat
蛋白分子量	40kDa
Gene ID	8600
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human TNF11
性状	液体
Public Immunogen Range	A synthetic peptide of human TNF11
Subcellular Locations	Cell membrane Nucleus Extracellular matrix
Swiss Prot	O14788
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis.