BRIP1 monoclonal antibody, clone pp15-IB4
产品名称: BRIP1 monoclonal antibody, clone pp15-IB4
英文名称: BRIP1 monoclonal antibody, clone pp15-IB4
产品编号: MAB2402
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic peptide of BRIP1.
- Immunogen:
- A synthetic peptide corresponding to human BRIP1.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody is specific to Brip1/FANCJ.
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In buffer containing 0.02% sodium azide
- Storage Instruction:
- Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24.
Kim JM, Kee Y, Gurtan A, D'Andrea AD.Blood. 2008 May 15;111(10):5215-22. Epub 2008 Jan 3.
- 2.
- Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.
Cannavo E, Gerrits B, Marra G, Schlapbach R, Jiricny J.J Biol Chem. 2007 Feb 2;282(5):2976-86. Epub 2006 Dec 4.
- 3.
- BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.
Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM.Cell. 2001 Apr 6;105(1):149-60.
- Entrez GeneID:
- 83990
- Gene Name:
- BRIP1
- Gene Alias:
- BACH1,FANCJ,FLJ90232,MGC126521,MGC126523,OF
- Gene Description:
- BRCA1 interacting protein C-terminal helicase 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations. [provided by RefSeq
- Other Designations:
- BRCA1-associated C-terminal helicase 1,BRCA1-binding helicase-like protein BACH1,BRCA1-interacting protein 1
- Related Disease
- Abortion, Spontaneous
- Adenocarcinoma
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Transitional Cell
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Disease Progression
- DNA Damage
- Edema
- Genetic Predisposition to Disease
- Glioma
- Lung Neoplasms
- Meningeal Neoplasms
- Meningioma
- Neoplasms
- Neoplasms, Glandular and Epithelial
- Neuroma, Acoustic